潘玉峰  教授，博士生導師

電話：025-83790776

E-mail: [email protected]

Labweb: panylab.org

辦公地點：南京市四牌樓2號，李文正北樓215室

個人簡介：

  2004年7月畢業(yè)于南開大學生物物理學專業(yè)獲得學士學位，2009年7月畢業(yè)于中國科學院生物物理研究所神經(jīng)生物學專業(yè)獲得博士學位。自2009年9月起在美國著名的霍華德休斯醫(yī)學研究所（Janelia Research Campus, Howard Hughes Medical Institute）做博士后工作。2014年受聘為東南大學生命科學研究院教授，2016年獲得國家優(yōu)秀青年基金以及江蘇省杰出青年基金?，F(xiàn)為東南大學首席教授、二級教授、博士生導師。

研究方向：動物行為的遺傳與神經(jīng)生物學機制

   行為是如何產(chǎn)生的？先天獲得的或是后天學習的？先天獲得、后天學習的神經(jīng)機制是什么？兩性行為的天然差異是如何產(chǎn)生的？不同行為之間的轉(zhuǎn)換與選擇（比如睡眠、覓食、求偶）在分子和神經(jīng)元水平的機制又是什么？本實驗室以經(jīng)典模式動物果蠅為模型，運用遺傳學、光遺傳學、行為學、分子生物學、電生理以及功能成像等技術(shù)手段研究動物行為的遺傳與神經(jīng)生物學機制。更多信息，請參見本實驗室主頁: panylab.org

代表性論文：

1.         Zhao, H., Jiang, X., Ma, M., Xing, L., Ji, X., and Pan, Y. (2024). A neural pathway for social modulation of spontaneous locomotor activity (SoMo-SLA) in Drosophila. PNAS, 121, e2314393121.

2.         Jiang, X., Sun, M., Chen, J., and Pan, Y. (2024). Sex-Specific and State-Dependent Neuromodulation Regulates Male and Female Locomotion and Sexual Behaviors. Research,7, 0321.

3.         Sun, M., Ma, M., Deng, B., Li, N., Peng, Q., and Pan, Y. (2023). A neural pathway underlying hunger modulation of sexual receptivity in Drosophila females. Cell Reports,42.113243.

4.         Ji, X., Li, X., Wang, L., Liu, S., Jiang, X., and Pan, Y. (2023). Asexuality in Drosophila juvenile males is organizational and independent of juvenile hormone. Embo Reports, e56898.

5.         Jiang, X., and Pan, Y. (2022). Neural Control of Action Selection Among Innate Behaviors. Neuroscience Bulletin,38, 1541-1558.

6.         Han, C., Peng, Q., Sun, M., Jiang, X., Su, X., Chen, J., Ma, M., Zhu, H., Ji, X., and Pan, Y. (2022). The doublesex gene regulates dimorphic sexual and aggressive behaviors in Drosophila. PNAS,119, e2201513119.

7.         Han, C., Peng, Q., Su, X., Xing, L., Ji, X., and Pan, Y. (2022). A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms. Communications Biology,5, 728.

8.         Peng, Q., Chen, J., and Pan, Y. (2021). From fruitless to sex: On the generation and diversification of an innate behavior. Genes Brain and Behavior,20, e12772.

9.         Jia, Y., Jin, S., Hu, K., Geng, L., Han, C., Kang, R., Pang, Y., Ling, E., Tan, E.K., Pan, Y.*, Liu, W.* (2021). Gut microbiome modulates Drosophila aggression through octopamine signaling. Nature Communications,12, 2698.

10.        Chen, J., Jin, S., Chen, D., Cao, J., Ji, X., Peng, Q., and Pan, Y. (2021). fruitless tunes functional flexibility of courtship circuitry during development. Elife,10, e59224

11.        Gao, C., Guo, C., Peng, Q., Cao, J., Shohat-Ophir, G., Liu, D., and Pan, Y. (2020). Sex and Death: Identification of Feedback Neuromodulation Balancing Reproduction and Survival. Neuroscience Bulletin,36, 1429-1440.

12.        Wu, S., Guo, C., Zhao, H., Sun, M., Chen, J., Han, C., Peng, Q., Qiao, H., Peng, P., Liu, Y., et al. (2019). Drosulfakinin signaling in fruitless circuitry antagonizes P1 neurons to regulate sexual arousal in Drosophila. Nature Communications,10, 4770.

13.        Zhang, W., Guo, C., Chen, D., Peng, Q., and Pan, Y. (2018). Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons. Neuroscience Bulletin,34, 1105-1110.

14.        Chen, D., Sitaraman, D., Chen, N., Jin, X., Han, C., Chen, J., Sun, M., Baker, B.S., Nitabach, M.N., and Pan, Y. (2017). Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila. Nature Communications,8, 154.

15.        Pan, Y., and Baker, B.S. (2014). Genetic identification and separation of innate and experience-dependent courtship behaviors in Drosophila. Cell,156, 236-248.

16.        Pan, Y., Meissner, G.W., and Baker, B.S. (2012). Joint control of Drosophila male courtship behavior by motion cues and activation of male-specific P1 neurons. PNAS,109, 10065-10070.